GENE/SNP

Allele

TFs

Protein name

# of Sites

TFBS

Strand

ADRBK1

rs948988 (A/G)

G

KLF1

Kruppel-like factor 1 (erythroid)

1

tgaCaCaCCga

minus

Intron 2

0.92

C = 100%

KLF4

Kruppel-like factor 4 (gut)

1

tcGGtGtgtc

plus

G = 98%

KLF5

Kruppel-like factor 5 (intestinal)

1

ccgaCtCCCc

minus

c = 87%

rs4370946 (C/T)

C

KLF4

Kruppel-like factor 4 (gut)

1

tGGGaGcGgg

minus

3’UTR

0.92

G = 90%

KLF5

Kruppel-like factor 5 (intestinal)

1

cccgCtCCCa

plus

c = 88%

SP1

Specificity Protein 1

1

tgcCCgCtccc

plus

C = 99%

SP1

Specificity Protein 1

1

cccgCtCCcag

plus

c = 77%

SP2

Specificity Protein 2

1

tgcCCgCtcccagtg

plus

C = 100%

TBXA2R

rs2238633 (A/C)

C

KLF4

Kruppel-like factor 4 (gut)

1

aGGGtGgGgt

minus

Intron 1

0.83

G = 90%

SP1

Specificity Protein 1

2

CcCcacCctgc

plus

c = 86%

rs4523 (C/T)

T

KLF4

Kruppel-like factor 4 (gut)

1

tGGGtGtata

minus

c.924T>C

0.45

t = 7%

Exon 3

rs5756 (C/T)

C

KLF4

Kruppel-like factor 4 (gut)

4

cGGGcGtggt

plus

3’UTR

0.63

G = 98%

VEGFA

rs1570360 (A/G)

G

KLF4

Kruppel-like factor 4 (gut)

2

gtGGaGgGGc

plus

Promoter

0.78

G = 98%

SP1

Specificity Protein 1

1

CCCcTCCACA

minus

c = 77%

rs34357231 (D/I)

I

KLF5

Kruppel-like factor 5 (intestinal)

1

gtccCaCtCt

plus

Promoter

0.28

KLF5

Kruppel-like factor 5 (intestinal)

1

actcttCCCa

plus

SP1

Specificity Protein 1

1

gtcCCaCtctt

plus

SP1

Specificity Protein 1

1

actCttCCcac

plus

(I)nsertation = 18bp (GGTCCCACTCTTCCCACA)